According to reports, Bunsen lost his glasses before shooting began. Fake glasses were bluescreened in. But for most of the shooting, he walked around the set partially blind, and knocked over pretty much everything around him. And apparently, he mistook Amy Adams' lamp for Beaker. He tried out one of his experiments on 'Beaker', ultimately causing the explosion from the scene where Gonzo destroys his building (it was planned to use stock footage for the explosion). Amy Adams was unhappy with what Bunsen did to her lamp, everybody else was unhappy with the damages they had to pay for, and Bunsen was eventually taken off of the set. Not even Crazy Harry was happy, apparently because he wasn't the cause of the explosion.