Follow that Bird had 2 antagonists... an antagonizing force (Finch), and a duo of villains (The Sleeze Brothers... I count them as one). Each had a connected part to the story... Finch trying to catch Big Bird due to her own self righteousness, The Brothers capturing him for their circus. I could say that would work pretty well in a Muppet film. Either 2 villains or one villain and one pain in the neck antagonist (like I said, a Zenegata character)Somebody suggested not having one main villian, and that might be a good idea. Maybe two or three seperate villians who are not associated with each other. Though I can't think of too many movies with those kinds of villians (Spiderman 3 is the only one I can think of), but it could be like the Batman movies where they have seperate villians who work on their own but eventually join the other villians and work together. But then if that was the case would the movie be required to give too much screentime to the villians to truly develop them (though it seems most of the villians in Muppet movies don't really get that much screen time)?
The thing is, Follow that Bird was pretty much like that. I think it would work well with the Muppets, only slightly changing it up a bit to not exactly resemble both films.This is what I've been saying. Hollywood's been wanting to remake It's a Mad, Mad, Mad, Mad World for a long time now - why not do it but with Muppets? It wouldn't be exactly the original plot (especially not that ending), but there's a way to do it. The only issue is that the Muppets would be split up for a bit, but it'd be neat to see certain team-ups.
Of course, we can have them split into teams to solve a mystery or capture a criminal. So they don't have to recycle the plot line of Mad Mad Mad Mad World exactly.