MMW was definitely a more modest success than its predecessor. I wouldn't go far as to call it a bomb, but it grossed slightly over its budget. Which is a little understandable because of its competition with Divergent. But the other problem I think was that the screenwriters merely played it a little bit too safe with the sequel, just mashing together elements of TGMC without having a more original plot, while the first had a more original story while giving it a more nostalgic feel. In other words lol, I think if MMW ended up being more like The Last Jedi, it probably would've attracted a lot more moviegoers. That being said, however, the Muppets have always had sort of a cult fanbase. It's not as big as Marvel's or Star Wars, so we've always been at sort of a disadvantage with the bigger studios and networks. (I know I've brought this up a couple times, but please bear in mind it took Jim a trip to LONDON to get TMS produced!)
MMW made back it's production budget, but a rule of thumb is that movies spend as much on advertising as they do on the production. Plus, you need to consider the movie theaters cut. It made 80 mil world wide, but that is gross not net. And as Mr. Price said, in terms of profit, you gotta be kidding with gross! Theaters usually take up to 45%. Being Disney, maybe they can strike a better deal of say 35%. That right there means that MMW barely made back production budget, or worse lost on the production budget, and certainly made nothing back on their advertising.
Personally, I liked MMW a lot. I like the extended cut way more than the theatrical cut. This is a problem many movies that should have done better have. Editing. MMW was chopped down too much and took out some key story elements that make the theatrical cut much worse than it is. Plus there is the timing of the release.
The Muppets cost 45 mil production, and made 165 mil world wide. That leaves 107 mil after theater's cut (assuming 35% for Disney bargaining power) Advertising is usually same as production costs for lets say total costs was 90. That leaves 17 mil profit. Not a huge smash hit, but the movie made money.
So yeah, MMW bombed even though its a good movie. To me it was more of a Muppet movie than The Muppets 2011.
Edit: But MMW didn't bomb as bad as MFS.... that thing lost the Jim Henson Company millions and kept the Muppets out of theaters for over a decade. I think the Muppets will likely not see another movie for at least another 4 years if not longer. Though, the backlash to Happy Time Murders might mean a new Muppet movie would be successful. There was so much hate towards that many people may go see a real Muppet movie to "fix their broken childhood". That is, if they understand the Happy Time murders was not actually the Muppets....