The South Park "Hare club for men" episode. Nuff said. Hillarious send up of "The DaVinci Code" and the Catholic Church. And while I doubt it's appropriate to tell how it really ends here, let's just say there's an unforgettible sequence with Jesus and Kyle.
I also love "Fat Albert's Easter Special." In this one, the junkyard Gang want to surprise their elderly friend Mudfoot Brown by cleaning out his house. Rudy pulls a prank that backfires, severly injuring and almost killing Mudfoot. It's a real tear jerker (especially the hospital scene where Mudfoot loses the will to live while being hooked up to life support), but it ends up quite happily. And it also is the only Fat Albert special to feature a Brown Hornet cartoon, the most important part.