Well, on the Nintendo Entertainment System, there was a Wacky Races game that was, oddly enough, a 2-D platformer (like Super Mario). It starred Muttley and you had to hop and bop your way through the levels, and the bosses were the other racers in their cars.
I think there was a Wacky Races video game on the 3DO in Japan, but I don't know anything about it.
Most recent Wacky Races games were on the Game Boy Color, Sega Dreamcast (and also for PS2 in Europe). These were bonafide racing games. You could pick from all the racers, and you really could use dragon power, getaway power, etc. Played a lot like Mario Kart.
--Klonoa
Before he passed away, I got to meet Don Messick. He said he could do Muttley's laugh better when he used to smoke!