I see YouTube changed the homepage design AGAIN...
They pretty much left the current layout of it the same, but the overall design is really hard on the eyes, and not very well-put together, it's almost like somebody who has no experience in web design basically tried to copy and reproduce the homepage layout himself.
EDIT: Oh gee, now we've got a new eye sore to contend with on the video pages as well: they've got this stack of icons to the left of the video player and they don't even tell you what they are, you can only assume what they do (one icon looks like a house, you can assume takes you to the homepage, another icon looks like a gear, assuming it's subscription settings or something)... it's certainly an annoyance if you use a 4:3 screen resolution like I do, but it seems like a weird play to put more useless do-hickeys, as opposed to, say, ABOVE or BELOW the video player.