That's clearly not going to happen here. The writers and director seem to have the same style of humor, and they're both working together. A GOOD movie has a symbiotic relationship with the writer and director. A bad one has the writer stick up a picture of the director on a dart board.
Your thoughts lately on all this remind me of something I proposed years ago on here: I had two ideas for Muppet films. One in which the Muppet gang was working in a dot com/tech company(which I guess now would be a facebook or google type place) and the opening scene would be like the madcap chaos in the first scenes of MFS. The other idea was a typical New York rom-com, played totally straight...but happening to have Pepe in it.
So I get giddy at the idea of sitting down in a theater, rolling my eyes at seeing yet another Vince Vaughn/Favreau/Jennifer Aniston/Seth Rogen/Apatow type comedy...but a minute into it, we see the person Vince Vaughn or Seth Rogen or Vince Vaughn is chewing out is Fozzie Bear. Now that'd be a sweet trailer,
where Nick Segal is having this argument in an apartment...and you think its going to be a girl or a guy friend he's talking to, and it happens to be a Muppet. And the audience has a "holy smokes, this is the new muppet movie!" moment.
As in, they treat it like they would a tentpole comedy film, and not the usual sacharine Disney family release.