Television to Muppets: "It's not you, it's ME!"
Television is in a strange state. While we're thankfully seeing less newly created reality shows, the staple reality programs just aren't budging. Action shows are stuck back to cop/investigation programs after the genre show slowly died (of course, it didn't help that Lost had such a stupid ending, The Event was a build up to "aliens did it" and no one cares about shows that don't even start the plot until halfway through the second season when they're canceled 5 episodes in). The sitcom, surprisingly, has made a comeback thanks in no small part to the Office. It is mostly cinematic, no laugh track/audience shows like The Middle and Raising Hope, as well as some mockumentary fair like Office, Parks and Rec and Modern Family. But the Laugh/audience show has made a comeback due to the likes of How I Met Your Mother (which I keep forgetting the laugh track/audience laughs because I barely notice them over the sounds of my own) and Chuck Lorre's Big Bang, Mike and Molly, and 2.5 Men.
I've also noticed that networks ONLY care about Sunday-Thursdays. You know a show's on the outs when they put it on Saturday Nights. They just stopped caring about Saturdays entirely and just rerun high rated shows from other nights. Other than SNL, of course. ABC doesn't even run "Wonderful World of Disney" movies anymore. It does movies, but usually PG-13 stuff and without the labels when it's family films. Fridays are Dodgey, but do-able. CBS has some stuff there... Fox has one original program and one rerun... there's stuff on Fridays, but it doesn't get the attention of the Monday-Thursday stuff... Sunday made a comeback years ago, though. Too bad everything gets pre-emptied by sports half the time.
The problem with a Muppet program on network TV is that either you get them in a completely too competitive to survive or an uncompetitive slot that's hard to regularly catch them in. ABC pretty much wrote off Fridays and put cheap reality shows in the slot (for a while they just re-ran Modern Family), so that wouldn't be that good a spot either. The Muppet Show survived 5 seasons on syndication (could have lasted more but it ended its run admirably with the creators saying they left on a high note), but there is no original programming on weekend syndication anymore (the 90's? sure... remember Hercules and Xena?). Muppets Tonight couldn't last on prime time network, and moved to a different time slot in its first season opposite 60 minutes. Second season was Disney channel exclusive and was shortly canceled. Disney Channel or ABC family would be ideal, EXCEPT for their demographics. Even if a Muppet Show were on Disney, it would be a LOT like Studio DC.