Tangled was a case of trying to make a "girly" sounding film more appealing to little boys. Considering the marketing of the film, I find that was a big mistake, since they made all the trailers come off as a late to the party Shrek knockoff. The film originally had a title to the extent of "Rapunzel Retangled."
I can kinda see where Disney went wrong with Princess and the Frog, releasing it too close to Chipmunks the Squeakual and Avatar. The fact they thought it was a blunder due to the film's title or the fact it was traditional animation was idiotic, since it was their fault they released the horrible Zemeckis Mo-Cap Christmas Carol in the cushy pre-Thanksgiving spot. had the dates been switched TP&TF would have at least made something more modest. But they took the blame as "Princess films come off too girly" and restructured Rapunzel's marketing and title. Then Winnie the Pooh came out, after years of turning it into a preschool, nay, prepreschool franchise. Because it was a preschool based film (even though it wasn't intended to be) it didn't do well (was packed when I saw it), and they threw their entire 2-D revival under the bus. Though to be fair, they gave us Wreck it Ralph, Big Hero Six, and Zootopia, so I can't get too mad about that.
Tangled did set it off, and I think that was the theme. They changed the stories so dramatically that Snow Queen barely had any resemblance to the tale, and Gigantic looks completely different other than having a giant and a beanstalk in it. Of course, Disney always changed things up, but those changes proved to be so popular, no no one remembers the original tales. Tweedles Dee and Dum are now forever associated with the wrong Alice book because of Disney.