Official estimates are in... not good:
http://www.boxofficemojo.com/weekend/chart/
Muppets went down even more to 16.5 million. Tomorrow the actuals come out, hopefully it'll rise, but in this case it seems more likely it'll drop even further.
For comparison, Peabody made about 11.7 mil on its third weekend (Muppets would be very lucky to catch that on its second), Lego did around 4 million in business on its seventh weekend (Muppets probably won't even be around for seven weekends), and Disney's own Frozen which stole a good amount of theaters away from Muppets managed to do .7 million on its 18th weekend. (MMW will be on DVD and Blu-Ray by then)
The domestic total will most likely wind up between 35 and 40 million, which means it needs at least 10 to 15 million overseas to not wind up a total flop... that isn't hard as I think MMW can do it. The real question is whether or not it can do extraordinarily better than that. Hope to god the answer is yes.
EDIT: Seems BoxOfficeMojo is already reporting a 1.5 mil overseas gross from this weekend
http://www.boxofficemojo.com/movies/?id=muppets2.htm
However, since there is no page up yet for foreign totals I have no idea where this is coming from. How many countries has it opened up in yet?